Calcium phosphates constitute the mineral component of bone and teeth in our bodies. The hollow and porous microspheres developed by Psilox AB are made up by the same substances, meaning that they are inherently biocompatible and bioresorbable carriers of ions required for bone and tooth remineralization. Due to their porous and hollow structure, the microspheres can also be loaded with e.g. an unprecedented amount of active pharmaceutical ingredients (APIs), providing an effective vehicle for drug delivery and controlled release.
Given the right conditions, the hollow calcium phosphate microspheres will grow spontaneously and precipitate out from a solution of salts, without the use of any surfactants or templates. This guarantees a material without any organic residues, born from a biomimetic mineralization process of biocompatible ions. The microspheres have been extensively characterized and evaluated for a range of biomedical applications, including tooth remineralization, tooth whitening, bone void filling, and drug delivery.
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